Insight into continuum couplings

Mitophagy: New Insight into the Cardiovascular Aging  

Comparison of solid-state dipolar couplings and solution relaxation data provides insight into protein backbone dynamics.

Analyses of solution (15)N relaxation data and solid-state (1)H(N)-(15)N dipolar couplings from a small globular protein, alpha-spectrin SH3 domain, produce a surprisingly similar pattern of order parameters. This result suggests that there is little or no ns-mus dynamics throughout most of the sequence and, in particular, in the structured portion of the backbone. At the same time, evidence of...

New Insight into the Relation between Adiponectin and Diabetes

Diabetes mellitus is a group of metabolic diseases. Insulin resistance is defined as a state that needs more insulin to get the biological effects achieved by a lower amount of insulin in the normal state. Several molecules which are secreted through adipocytes have been involved in insulin resistance and type 2 diabetes mellitus. Adiponectin as a 244 amino acid protein is exclusively expressed...

Newt insight into regeneration

1 0. 10 83 /j cb. 17 23 it i3 j cb 17 23 it i3 Nicole [email protected] ewt ins ight into regenerat ion L imb regeneration, as seen in amphibians, might not be as far from humanly possible as once thought. On page 433 , Morrison et al. show that the regeneration of newt limbs hinges on the activation of muscle satellite cells—t...

New insight into superconductivity

NOVEMBER 2008 | VOLUME 11 | NUMBER 11 13 The physics of high-temperature cuprate superconductors in the overdoped regime, where superconductivity is suppressed, is something of a mystery. But first-principle calculations by researchers in the US and Switzerland appear to confirm a recent suggestion that ferromagnetism can destroy superconductivity at high doping levels [B. Barbiellini and T. Ja...